Initial Gleason score does not predict abiraterone response in patients with metastatic castration-resistant prostate cancer

Initial Gleason score does not predict abiraterone response in patients with metastatic castration-resistant prostate cancer

0:00
12 February 2014

SAN FRANCISCO— Gleason score at initial diagnosis was not predictive of response to abiraterone in patients with metastatic castration-resistant prostate cancer in a pooled analysis of three trials of

SAN FRANCISCO— Gleason score at initial diagnosis was not predictive of response to abiraterone in patients with metastatic castration-resistant prostate cancer in a pooled analysis of three trials of abiraterone acetate therapy presented at the 2014 ASCO Genitourinary Cancers Symposium. Karim Fizazi MD PhD, Professor of Medicine and Head of the Department of Cancer Medicine at the Institut Gustave Roussy in Villejuif, Paris, discussed his group’s findings and the implications for using new generation androgen deprivation therapy in the advanced stages of prostate cancer.

CONTACT:
Dr. Karim Fizazi MD PhD
Head of the Department of Cancer Medicine
Institut Gustave Roussy, Villejuif, Paris

SOURCE:
Does Gleason score (GS) predict efficacy of abiraterone acetate (AA) therapy in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC)? An analysis of AA phase 3 trials.

LINK:
Web link: http://meetinglibrary.asco.org/content/123754-142

TAGS:
Gleason score, abiraterone, metastatic castration-resistant prostate cancer, ASCO GU 2014 Symposium San Francisco, anti-androgen therapy, androgen deprivation,

Related Episodes

Jefferson DeKloe BSc: Big US Study Confirms Benefit of HPV Vaccination for Boys as Well as Girls

Jefferson DeKloe BSc: Big US Study Confirms Benefit of HPV Vaccination for Boys as Well as Girls

The cancer prevention benefit of vaccination against the human papilloma virus cancer prevent are slowly accruing thanks to European, American and other population-based studies.  I’m Peter Goodwin wi

1 October 2025
6:07
More
Luis Paz-Ares MD PhD: Longer Survival Among Patients with Extensive Stage Small Cell Lung Cancer Treated with Lurbinectedin Maintenance —ASCO 2025

Luis Paz-Ares MD PhD: Longer Survival Among Patients with Extensive Stage Small Cell Lung Cancer Treated with Lurbinectedin Maintenance —ASCO 2025

Luis G Paz-Ares MD PhD discdusses the addition of lurbinectedin as maintenance therapy for extensive stage small cell lung cancer (SCLC)

30 June 2025
11:51
More
Frank A Sinicrope MD: Stage 3 Colon Cancer with Deficient Mismatch Repair: Big Gains from Atezolizumab Added to Standard Chemotherapy

Frank A Sinicrope MD: Stage 3 Colon Cancer with Deficient Mismatch Repair: Big Gains from Atezolizumab Added to Standard Chemotherapy

An interview with: Frank A Sinicrope, MD, Medical Oncologist, Mayo Clinic, Rochester, Minnesota. CHICAGO —Big gains in survival have been reported among patients with stage three, node-positive colon

10 June 2025
7:24
More