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  1. Time from nephrectomy to metastasis confirmed as prognostic in patients with renal cell carcinoma treated with targeted therapies
    Audio Journal of Oncology

    Time from nephrectomy to metastasis confirmed as prognostic in patients with renal cell carcinoma treated with targeted therapies

    SAN FRANCISCO—The length of time from nephrectomy up until the diagnosis of metastatis has been confirmed as prognostic for patients whose renal cell carcinoma was treated with targeted therapies — ju

    13/02/2014
    Details
  2. Initial Gleason score does not predict abiraterone response in patients with metastatic castration-resistant prostate cancer
    Audio Journal of Oncology

    Initial Gleason score does not predict abiraterone response in patients with metastatic castration-resistant prostate cancer

    SAN FRANCISCO— Gleason score at initial diagnosis was not predictive of response to abiraterone in patients with metastatic castration-resistant prostate cancer in a pooled analysis of three trials of

    12/02/2014
    Details
  3. Responses to enzalutamide after prior abiraterone therapy in men with castration-resistant metastatic prostate cancer
    Audio Journal of Oncology

    Responses to enzalutamide after prior abiraterone therapy in men with castration-resistant metastatic prostate cancer

    SAN FRANCISCO— Four out of ten patients whose metastatic castration resistant prostate cancer had already been treated with abiraterone responded to further ‘new generation’ androgen depri

    11/02/2014
    Details
  4. PSA-membrane antibody conjugate shows promise for treating metastatic castration-resistant, taxane-refractory prostate cancer
    Audio Journal of Oncology

    PSA-membrane antibody conjugate shows promise for treating metastatic castration-resistant, taxane-refractory prostate cancer

    SAN FRANCISCO—A “guided missile” approach to treating metastatic, castration-resistant, taxane-refractory prostate cancer demonstrated success at the 2014 ASCO Genitourinary Cancers Sympos

    06/02/2014
    Details
  5. Orteronel shows no survival advantage in metastatic castration-resistant prostate cancer: phase III randomized study finds
    Audio Journal of Oncology

    Orteronel shows no survival advantage in metastatic castration-resistant prostate cancer: phase III randomized study finds

    SAN FRANCISCO—Orteronel — a non-steroidal selective inhibitor of 17,20-lyase — did not achieve a significant improvement in overall survival in 1099 patients randomised to treatment with this “a

    06/02/2014
    Details
  6. Idelalisib: new targeted therapy improves outlook for patients with chronic lymphocytic leukaemia
    Audio Journal of Oncology

    Idelalisib: new targeted therapy improves outlook for patients with chronic lymphocytic leukaemia

    NEW ORLEANS—A new oral tyrosine kinase inhibitor drug — idelalisib — has proved effective — and to have low toxicity — in patients with chronic lymphocytic leukaemia (CLL). Richard Furman MD from Weil

    24/01/2014
    Details
  7. First effective treatment for “orphan disease’: Anti I/L 6 antibody brings remissions in Multicentric Castleman’s Disease
    Audio Journal of Oncology

    First effective treatment for “orphan disease’: Anti I/L 6 antibody brings remissions in Multicentric Castleman’s Disease

    The rare, fatal lympho-proliferative condition: Multicentric Castleman’s Disease — MCD — could soon be treatable following findings announced at the American Society of Hematology annual meeting

    21/01/2014
    Details
  8. HAND2 gene: key to endometrial, ovarian cancer detection and treatment individualisation
    Audio Journal of Oncology

    HAND2 gene: key to endometrial, ovarian cancer detection and treatment individualisation

    LONDON— Researchers have shown that endometrial cancer — and hopefully ovarian cancer too — could potentially be detected much earlier than at present — or even prevented altogether — by looking for &

    15/01/2014
    Details
  9. Chimeric antigen receptor T-cell therapy: high remission rate in relapsed, refractory acute lymphoblastic leukemia
    Audio Journal of Oncology

    Chimeric antigen receptor T-cell therapy: high remission rate in relapsed, refractory acute lymphoblastic leukemia

    NEW ORLEANS—High remission rates with extended survival are being achieved in patients who had failed all other therapies — including allogeneic stem cell transplantation — for their acute lymphoblast

    19/12/2013
    Details
  10. PDL1 inhibitor brings better responses in smokers with refractory lung cancer
    Audio Journal of Oncology

    PDL1 inhibitor brings better responses in smokers with refractory lung cancer

    AMSTERDAM— New hopes for smokers with lung cancer were raised at the 2013 European Cancer Congress here by research findings from France, Spain and the USA using a new form of immunotherapy to treat r

    19/11/2013
    Details
  11. Prostate cancer screening: French study finds more harm than good from PSA testing
    Audio Journal of Oncology

    Prostate cancer screening: French study finds more harm than good from PSA testing

    AMSTERDAM— Organized screening for prostate cancer using the prostate-specific antigen (PSA) test does more harm than good, according to the findings of a French study reported here at the 2013 Europe

    19/11/2013
    Details
  12. The TH3RESA study: TDM-1 doubles progression free survival in HER-2 positive refractory metastatic breast cancer.
    Audio Journal of Oncology

    The TH3RESA study: TDM-1 doubles progression free survival in HER-2 positive refractory metastatic breast cancer.

    AMSTERDAM—Women with HER-2 positive metastatic breast cancer had significantly improved time to progression with fewer side effects after treatment with the antibody-drug conjugate T-DM1 compared to c

    19/11/2013
    Details
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